Updates on World Health Organization classification and staging of esophageal tumors: implications for future clinical practice

نویسندگان

چکیده

The Fifth edition of the World Health Organization classification digestive system and American Joint Committee on Cancer staging manual contain substantial refinements information for esophageal tumors. epithelial tumors esophagus are classified as benign, dysplasia, malignant groups. Dysplasia is divided into Barrett dysplasia squamous graded either low-grade or high-grade. Malignant often adenocarcinoma cell carcinoma. main update in cancer subdivision prognostic 3 groups; carcinoma, adenocarcinoma, carcinoma after adjuvant therapy. HER-2 amplification recognized a molecular target therapy esophagogastric adenocarcinoma. other adenoid cystic mucoepidermoid/adenosquamous undifferentiated neuroendocrine neoplasms. Overall, incorporation new data definitions histopathology, factors, genetics important personalized management patients with

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ژورنال

عنوان ژورنال: Human Pathology

سال: 2021

ISSN: ['0046-8177', '1532-8392']

DOI: https://doi.org/10.1016/j.humpath.2020.10.015